HLA in Narcolepsy

HLA in Narcolepsy

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The Second International Symposium on Narcolepsy was held at Fairchild Auditorium, Stanford University, on 6-7 July 1985 under the presidency of Drs. William C. Dement and Christian Guillemi nault. It succeeded the First International Symposium on Narco lepsy held in La Grande Motte, France, organized by Pierre Pas souant in July 1975 in commemoration of the 100th anniversary of the publication of Jean B. E. Gelineau's paper which proposed the naming of narcolepsy. At the second narcolepsy symposium, many important research reports on both basic and clinical aspects of narcolepsy were given by investigators from many countries of the world. Audience inter est was particularly attracted by the section on the relationship be tween HLA and narcolepsy, in which recent evidence that almost all narcoleptic patients are HLA-DR2 positive was reported by in vestigators from Japan, England, France, Canada, and the United States. The close relationship between the HLA antigens, hitherto considered as immune-related genetic markers encoded by genes on human chromosome 6, and narcolepsy appeared to open a new approach not only for the research of narcolepsy but also for the mechanism of sleep in general. Publication of all these new findings on the association of HLA and narcolepsy was considered; an outline was worked out and all the groups agreed to prepare a contribution covering the various aspects of this topic.Yutaka Honda, Takeo Juji. Family J . . . A32 || A10 B12 | B21 DR2 || a€“ A9 A32| A10 A32| A10 A10 || A10 B7 B12 | B12 B12 | B12 B21 B12 DR2 DR2 DRI, DR2 DR4 - | DR4 l i A32 B12 B8 DR2 DR1 DR2| DR3 DR2||DR2 DR3| DR4 Danbsp;...


Title:HLA in Narcolepsy
Author: Yutaka Honda, Takeo Juji
Publisher:Springer Science & Business Media - 2012-12-06
ISBN-13:

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